| 陈必婷1
，梁振益1
，温珍昌1
，郭志凯2,3
，徐 静1*.红树林来源内生真菌活性产物研究进展[J].海南师范大学学报自科版,2022,35(4):373-385 |
| 红树林来源内生真菌活性产物研究进展 |
| Research Progress on Bioactive Products from Mangrove-derivedEndophytic Fungi |
| |
| DOI： |
| 中文关键词: 红树林 内生真菌 次级代谢产物 生物活性 药用价值 |
| 英文关键词: mangrove plants endophytic fungi secondary metabolites biological activities medicinal values |
| 基金项目:海南省重大科技项目（ZDKJ202008/ZDKJ202018）；海南省重点研发项目（ZDYF2021108）；国家自然科学基金
项目（81973229/82160675）；广东省海洋药物重点实验室开放课题（LMM2021-4） |
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| 摘要点击次数: 791 |
| 全文下载次数: 1911 |
| 中文摘要: |
| 红树林植物是生长于热带和亚热带海岸和河口潮间带的木本植物群落，海陆边缘生态
系统的独特生境使得红树林来源内生真菌具有独特的遗传背景和代谢途径，蕴藏着结构新颖、活
性显著的次级代谢产物。本文综述了近年来红树林来源内生真菌代谢产物的结构特点及抗肿瘤、
抗炎和抗菌等生物学功能的研究进展，以期为红树内生真菌来源新型天然药物的开发提供参考。 |
| 英文摘要: |
| Mangrove plants are widely distributed in the transition zone along tropical and sub-tropical estuaries or coast⁃
lines worldwide. Endophytic fungi communities from mangrove habitats of extreme environmental condition have apparently
evolved over eons and developed unique genetic background and metabolic pathways, which have demonstrated to be a pro⁃
lific reservoir of structurally novel and active natural products. This review summarizes the research progress on characteris⁃
tics of various natural products from mangrove-derived endophytic fungi and the related biological activities such as antitu⁃
mor, anti-inflammatory and antimicrobial activities, the medicinal application potential were highlighted. |
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