| 张永康，周晓虎，陈业高.狗牙花生物碱成分的研究[J].海南师范大学学报自科版,2019,32(2):124-127 |
| 狗牙花生物碱成分的研究 |
| Study on the Alkaloid Composition of Ervatamia divaricata (L.) Burk. 'Gouyahua' |
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| DOI：10.12051/j.issn.1674-4942.2019.02.002 |
| 中文关键词: 狗牙花 化学成分 结构鉴定 |
| 英文关键词: Ervatamia divaricata (L.) Burk. 'Gouyahua' alkaloids structure identification |
| 基金项目:云南省高校药用活性分子结构多样性研究重点实验室（2016-5） |
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| 中文摘要: |
| 狗牙花（Ervatamia divaricata（L.）Burk. 'Gouyahua'）枝叶用丙酮提取，利用硅胶柱层析、
Sephadex LH-20柱层析和反相柱层析进行化学成分分离纯化，从中分离得到6个吲哚生物碱。根
据波谱技术和理化性质对化合物结构进行鉴定，鉴定结构为：coronaridine（1）、19-epi-heyneanine
（2）、isovoacangine（3）、ibogamine（4）、19（S）-hydroxyibogamine（5）和 apparicine（6），其中化合物2、 3和5为首次从该植物中分离得到。 |
| 英文摘要: |
| :Six indole alkaloids were extracted from the acetone extract of the twigs and leaves of Ervatamia divaricata (L.)
Burk. 'Gouyahua' and isolated and purified by silica gel chromatography, Sephadex LH-20 chromatography and reversedphase chromatography. With spectroscopic analysis combined with their physicochemical data, the structures of these in⁃
dole alkaloids were identified as coronaridine (1), 19-epi-heyneanine (2), isovoacangine (3), ibogamine (4), 19(S)-hydroxy⁃
ibogamine (5), apparicine (6). Among these compounds, compound 2, 3 and 5 were obtained from Ervatamia divaricata (L.)
Burk. 'Gouyahua' for the first time. |
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